Medication and anemia
A healthy kidney helps to control blood production: it contributes to produce hemoglobin through EPO (erythropoietin) secretion which stimulates red blood cell production.
EPO (Erythropoietin) and Iron
EPO is an hormone produced by healthy kidneys which stimulates bone marrow to produce red blood cells, a constituent from blood which transports oxygen around the body.
In Renal disease, once kidneys begin to fail, EPO production by kidney starts to decrease, leading to less circulating red blood cells. This problem is called anemia, and it makes a person feel tired, with pale skin and cold, among other symptoms.
EPO is prescribed to correct anemia. It is administrated during hemodialysis treatment by injection in the skin (subcutaneous) or by intravenous administration on the dialysis machine.
Iron is a constituent from red blood cells, its administration may be needed during dialysis to adjust body production.